Gene syntax alters DNA supercoiling to amplify or suppress nearby genes. This could improve the effectiveness of gene ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily. So for ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Scientists at Stanford University have discovered that DRT3, a unique defense system found in bacteria, creates DNA to ...

Scientists developed a charge-free polymer-DNA complex that boosts cellular DNA uptake 14-fold in mice, avoiding the harmful inflammation caused by current methods. Many existing options rely on ...

Researchers used tiny DNA-based molecules to cut levels of LDL (bad) cholesterol by nearly 50% in animal models. This was ...

The newest DNA sequencing technology from Swiss multinational Roche doesn’t measure DNA directly but in fact analyzes a different polymer altogether. The technology is not yet available for sale, but ...

Cancer cells survive by repairing damage to their DNA—even damage that would normally be fatal. One of their most important ...

New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our ...

Schematic showing a single DNA duplex bridging two gold electrodes (yellow) patterned on a silicon nitride substrate (green). The setup allows measurement of electrical conductance as metal ions bind ...