Mar 31, 2025 · The best antibiotic depends on your infection type, health, and local resistance patterns. Common first choices include azithromycin, clarithromycin, or doxycycline.

Mar 7, 2024 · Antibiotics shouldn't be your first choice if you have a sinus infection because most of these infections are caused by viruses, and antibiotics only work on bacteria.

Aug 14, 2025 · On the basis of clinical practice guidance from the American Academy of Otolaryngology - Head and Neck Surgery, amoxicillin with or without clavulanate should be the first antibiotic therapy...

Nov 12, 2025 · What are the best antibiotics for a sinus infection? The antibiotic that’s best for your bacterial sinus infection will depend on your medication allergies and how severe your symptoms are.

Jun 11, 2025 · Typically, an antibiotic in the penicillin class is the starting point unless you have a history of frequent sinus infections or immunosuppression. Amoxicillin or amoxicillin-clavulanic acid …

May 28, 2025 · Studies have compared the efficacy of different antibiotics in treating sinus infections: The optimal duration of treatment for sinus infections is unknown, but some studies recommend …

View the AAFP Choosing Wisely recommendation on prescribing antibiotics to treat sinusitis.

Oct 22, 2025 · Antibiotics such as amoxicillin, doxycycline, and levofloxacin can be prescribed to treat acute or chronic bacterial sinusitis, helping to eliminate bacteria and reduce sinus inflammation. …

Nov 10, 2023 · Antibiotics for sinus infections, such as amoxicillin, doxycycline, or levofloxacin, can be prescribed by a doctor to treat cases of acute or chronic bacterial sinusitis. These help to eliminate …

Aug 16, 2025 · Right now, three antibiotics are the main heavyweights: amoxicillin-clavulanate, doxycycline, and levofloxacin. Amoxicillin-clavulanate has held the crown for years, but the line-up …